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Bone Marrow Transplant Bone Marrow Transplant

What is a Bone Marrow Transplant?

Haematopoietic or blood-forming stem cells are ‘’Mother’’ cells that can mature into the various form of blood cells; largely the red cells, white cells and platelets. These stem cells are found in the bone marrow and umbilical cord blood and can be driven into the blood stream after chemotherapy or growth factor stimulation.

Bone marrow transplantation is more properly defined as haematopoeitic bone marrow transplantation or haemopoeitic stem cell transplantation because these cells can be harvested from the bone marrow, peripheral blood, umbilical cord blood. The sources of these haemopoeitic stem cells may be a compatible family member or an unrelated donor (allogeneic transplantation), an identical twin (syngeneic transplantation) or the patient’s own cells previously collected and suitably stored (autologous transplantation)

The transplant services we offer include the two major categories of transplants - autologous and allogeneic bone marrow transplants.

Autologous bone marrow transplant

The autologous bone marrow transplant, more appropriately called stem cell rescue, makes it possible to treat patients with malignancies with high dose chemotherapy. It is important for the group of patients whose diseases had relapsed despite standard chemotherapy but who can be cured with high dose chemotherapy. The stem cells could be either harvested from the marrow directly or collected from the peripheral blood following chemotherapy with or without growth factors.

Allogeneic bone marrow transplant

Allogeneic bone marrow transplantation with matched sibling donors, matched unrelated donors and haplo-identical donors are fairly well established in the treatment of many haematologic malignancies, severe aplastic anaemia (marrow failure) and severe immunodeficiency diseases. Allogeneic transplant not only allowed high dose chemotherapy to be given but also allowed restoration of marrow function and immunity in patients whose marrow function had been damaged by disease eg acute leukemias. The donor stem cells, and immune cells also provide an anti-tumor effects to prevent the disease from relapsing

Why get a Bone Marrow Transplant

A Bone Marrow transplant provides better outcomes and survival rate for diseases such as acute leukaemias, lymphomas, multiple myeloma and severe aplastic anaemias. Stem cell transplant is the only cure for thalassaemia major and sickle cell disease.

  • Medical Expertise
  • Personalised Care
  • State Of The Art Medical Equipment

Our expert team at Mount Elizabeth consists of specialists who offer a complete range of medical and surgical interventions including acute and chronic disease management, end-stage disease management, and stem cell and bone marrow transplant. Our experts have the capability and experience to undertake transplantations such unrelated donor transplant, Haplo-identical transplant, Umbilical cord blood transplant and in certain circumstances Mismatched transplants.

We have a transplant unit designated to provide transplant patients with comprehensive and specialised care. The transplant unit has a committed inpatient ward with Intensive Care Unit facilities for seamless post-surgery care.

You are and will always be our priority. Getting a bone marrow transplant may offer you the following advantages:

  • A better quality of life, as the transplant can be scheduled.
  • Better survival outcomes.
  • Safely allow treatment of your condition with high doses of chemotherapy or radiation by replacing or rescuing the bone marrow damaged by treatment.
  • Replace diseased or damaged marrow with new stem cells.

We have a transplant unit designed to provide transplant patients with comprehensive and specialised care. The transplant unit has a dedicated inpatient ward with Intensive Care Unit facilities for seamless post-surgery care. Our team of specialised ICU nurses are well-trained to support patients through the entire process from treatment to post-transplant monitoring and recovery.

Undergoing a Bone Marrow Transplant

Our teams of experts will take you through each step of the process outlined below:

Treatment Guidelines

Our team of medical experts will take you through every step of the process. The guide below is a general overview of how the case will go:

1. Treatment Planning

Treatment Planning

2. Disease, Fitness and Organ Function Assessment

Disease, Fitness and Organ Function Assessment

3. Bone Marrow Collection

bone marrow collection

4. Bone Marrow Infusion

Stem Cells Infusion

5. Post transplant
management

Post transplant management

6. Discharge and Monitoring

Discharge and Monitoring

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For urgent medical assistance, call our 24-hour A&E Helpline at +65 6731 2218 (Orchard), or +65 6933 0100 (Novena).